As a result of metabolic processes during the digestion of proteins, organic acids arise and develop. These acids produce cellular energy and form fundamental elements necessary for cell functioning.

Measuring the added acid content allows the clinician to perform a functional assessment of nutritional care. High acid levels in urine can cause inhibition or blockage due to natural enzyme deficiencies, nutrient levels, toxin buildup, or medications. Vitamins and minerals are required for sufficient levels of enzymes prepared to measure acids. Thus, increased urinary acidity may reflect a functional requirement for these nutrients at the cellular and biochemical level, even if serum analysis shows normal results. Based on the results of the analysis, the doctor can make recommendations for taking nutrients.

For which patients is the organic acid test best used?

The organic acid test should be considered in patients who experience symptoms such as:

• mood swings
• mitochondrial dysfunction
• come
• chronic stress
• add

As the level increases, there is increased acidity and other diseases, such as diabetes, cardiovascular disease, depression, anorexia, anxiety, decreased neurocognitive function, cancer and some others.

What does the organic acid test measure?

The test determines the content of more than 50 acids in a urine sample. The profile report categorizes analysis results into six main metabolic areas:

• Malabsorption and dysbiosis markers are manifested by pathological waste products and fungi in the gastrointestinal tract. In the absence of dysbiosis, high levels of these metabolites may indicate good consumption of foods rich in antioxidants.
• Cellular energy and mitochondrial markers: abnormal acid levels associated with the Krebs cycle provide insight into various conditions and experimental targets for correction of mitochondrial dysfunction.
• Vitamin markers are acid markers commonly used to determine B vitamin status. Doctors can provide insight into reasonable vitamin requirements by measuring the levels of these acids, which are known to come from specific nutrients through enzymatic metabolism.
• Neurotransmitter metabolites are measured acid markers that represent secondary metabolites of neurotransmitter synthesis and degradation. Elevated levels may indicate amino acid supply of neurotransmitters due to the need for enzymatic cofactors, chronic disease, stress, genetic predisposition, and toxins.
• Toxins and Detoxification markers: These organic acids are markers of exposure to environmental toxins or upregulation of detoxification pathways in response to exposure. Increasing these levels leads to acid recommendations to identify exposure factors and minimize or eliminate them.
• Oxalate markers: These organic acids may indicate metabolic disorders leading to increased levels of oxalic acid. Oxalates may be of particular clinical importance for patients suffering from recurrent kidney stones, since high oxalic acid levels are a major risk factor for the development of kidney stones.

Organic acids in uric technology using highly sensitive methods of gas chromatography-mass spectrometry (GC-MS) and liquid chromatography with a tandem mass spectrometry setup (LC/MS/MS). Reference ranges are age- and sex-specific and are based on questionnaires from a healthy cohort.

What type of sample is needed to perform the organic acid test?

The test requires a urine sample taken early in the morning. Fasting is necessary at night. Four days before the test, the doctor and some clinicians prefer to stop taking non-essential nutritional supplements to obtain a baseline, while others continue to take supplements to assess the effectiveness of treatment.

Пример результата исследования

As a result of metabolic processes during the digestion of proteins, organic acids arise and develop. These acids produce cellular energy and form fundamental elements necessary for cell functioning.

Measuring the added acid content allows the clinician to perform a functional assessment of nutritional care. High acid levels in urine can cause inhibition or blockage due to natural enzyme deficiencies, nutrient levels, toxin buildup, or medications. Vitamins and minerals are required for sufficient levels of enzymes prepared to measure acids. Thus, increased urinary acidity may reflect a functional requirement for these nutrients at the cellular and biochemical level, even if serum analysis shows normal results. Based on the results of the analysis, the doctor can make recommendations for taking nutrients.

For which patients is the organic acid test best used?

The organic acid test should be considered in patients who experience symptoms such as:

• mood swings
• mitochondrial dysfunction
• come
• chronic stress
• add

As the level increases, there is increased acidity and other diseases, such as diabetes, cardiovascular disease, depression, anorexia, anxiety, decreased neurocognitive function, cancer and some others.

What does the organic acid test measure?

The test determines the content of more than 50 acids in a urine sample. The profile report categorizes analysis results into six main metabolic areas:

• Malabsorption and dysbiosis markers are manifested by pathological waste products and fungi in the gastrointestinal tract. In the absence of dysbiosis, high levels of these metabolites may indicate good consumption of foods rich in antioxidants.
• Cellular energy and mitochondrial markers: abnormal acid levels associated with the Krebs cycle provide insight into various conditions and experimental targets for correction of mitochondrial dysfunction.
• Vitamin markers are acid markers commonly used to determine B vitamin status. Doctors can provide insight into reasonable vitamin requirements by measuring the levels of these acids, which are known to come from specific nutrients through enzymatic metabolism.
• Neurotransmitter metabolites are measured acid markers that represent secondary metabolites of neurotransmitter synthesis and degradation. Elevated levels may indicate amino acid supply of neurotransmitters due to the need for enzymatic cofactors, chronic disease, stress, genetic predisposition, and toxins.
• Toxins and Detoxification markers: These organic acids are markers of exposure to environmental toxins or upregulation of detoxification pathways in response to exposure. Increasing these levels leads to acid recommendations to identify exposure factors and minimize or eliminate them.
• Oxalate markers: These organic acids may indicate metabolic disorders leading to increased levels of oxalic acid. Oxalates may be of particular clinical importance for patients suffering from recurrent kidney stones, since high oxalic acid levels are a major risk factor for the development of kidney stones.

Organic acids in uric technology using highly sensitive methods of gas chromatography-mass spectrometry (GC-MS) and liquid chromatography with a tandem mass spectrometry setup (LC/MS/MS). Reference ranges are age- and sex-specific and are based on questionnaires from a healthy cohort.

What type of sample is needed to perform the organic acid test?

The test requires a urine sample taken early in the morning. Fasting is necessary at night. Four days before the test, the doctor and some clinicians prefer to stop taking non-essential nutritional supplements to obtain a baseline, while others continue to take supplements to assess the effectiveness of treatment.

Пример результата исследования